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1.天津中医药大学实验针灸学研究中心(天津 301617)
2.天津中医药大学针灸推拿学院(天津 301617)
3.国家中医针灸临床医学研究中心(天津 300193)
4.天津市现代中医理论创新转化重点实验室(天津 301617)
骆雨,女,硕士研究生,主要从事神经免疫学方向的针刺作用机制研究
徐枝芳,研究员,博士研究生导师; E-mail: xuzhifangmsn@hotmail.com
纸质出版日期:2024-09-10,
收稿日期:2023-11-13,
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骆雨,姚港林,李姗姗,等.基于数据挖掘探析针药结合治疗哮喘的临床优势与针灸选穴规律[J].上海中医药杂志,2024,58(9):6-12.
LUO Yu,YAO Ganglin,LI Shanshan,et al.Data mining⁃based analysis of clinical advantages of combining acupuncture and medicines in treating asthma and acupoint selection rules[J].Shanghai Journal of Traditional Chinese Medicine,2024,58(9):6-12.
骆雨,姚港林,李姗姗,等.基于数据挖掘探析针药结合治疗哮喘的临床优势与针灸选穴规律[J].上海中医药杂志,2024,58(9):6-12. DOI: 10.16305/j.1007-1334.2024.2311073.
LUO Yu,YAO Ganglin,LI Shanshan,et al.Data mining⁃based analysis of clinical advantages of combining acupuncture and medicines in treating asthma and acupoint selection rules[J].Shanghai Journal of Traditional Chinese Medicine,2024,58(9):6-12. DOI: 10.16305/j.1007-1334.2024.2311073.
目的
2
系统梳理针药结合治疗哮喘的临床研究文献,利用数据挖掘探讨其潜在的临床优势与针灸选穴规律。
方法
2
检索收录在中国知网、维普资讯中文期刊服务平台、万方数据知识服务平台、中国生物医学文献数据库及 PubMed、Web of Science、Embase、Scoups等数据库中的近20年临床研究文献,建立“针药结合治疗哮喘数据库”,运用频数统计及SPSS Modeler 18.0、Gephi0.10.1软件进行文献挖掘分析。
结果
2
①针刺优势以靶器官功能与多项血生化指标(免疫功能指标、血清炎症因子)的调节为主;中药优势为能进一步增强肺通气功能;针刺与中药联合应用可显著提高哮喘患者临床疗效。②针刺治疗哮喘重要程度排名前5位的腧穴依次为肺俞、定喘、足三里、肾俞、膻中,关联规则分析显示定喘-肺俞支持度最高,其次为脾俞-肺俞;足太阳膀胱经与手太阴肺经为常用经脉。③体现针刺优势的腧穴处方重视局部选穴,循经选穴,上下配穴。
结论
2
针药结合治疗哮喘是提高疗效的主要原因,其临床优势在于局部与整体兼顾,“标本同治,从肺论治,局部选穴,远近配穴”的临床取穴规律是针刺优势的体现之一,这为针药结合的科学应用提供了新思路。
Objective
2
To systematically review clinical research literature on the combination of acupuncture and medicines for the treatment of asthma, and discuss its potential clinical advantages and acupoint selection rules based on data mining.
Methods
2
Clinical researchs from the past 20 years were retrieved from databases, including China National Knowledge Infrastructure (CNKI), WanFang Data, Chinese Scientific Journal Database (VIP), SinoMed, PubMed, Web of science, Embase, and Scoups. A “Database on Treating Asthma with Combination of Acupuncture and Medicines” was established, with frequency statistics and tools like SPSS Modeler 18.0 and Gephi 0.10.1 used for data analysis.
Results
2
①The advantage of acupuncture primarily lay in the regulation of target organ functions and multiple blood biochemical indicators (such as immune function indicators and serum inflammatory factors); the advantage of Chinese medicines was their ability to further enhance pulmonary ventilation functions; the combined use of acupuncture and Chinese medicines could significantly improve the clinical efficacy in asthma patients. ②The top five acupoints in the importance ranking for treating asthma with acupuncture were Feishu (BL13), Dingchuan (CV22), Zusanli (ST36), Shenshu (BL23), and Danzhong (CV17). Association rule analysis showed that the highest support was for Dingchuan (CV22)-Feishu (BL13), followed by Pishu (BL20)-Feishu (BL13), and the Bladder Meridian of Foot Taiyang and the Lung Meridian of Hand Taiyin were the most commonly used meridians. ③The acupoint prescriptions that can demonstrate the advantages of acupuncture emphasized local point selection, meridian-based point selection, and upper and lower points coordination.
Conclusions
2
The combination of acupuncture and medicines for asthma treatment is a major factor in improving therapeutic efficacy. Its clinical advantage lies in balancing both local and holistic aspects. The clinical practice of treating both symptoms and root causes, focusing on the lungs, selecting local points, and combining distant and nearby points reflects one of the advantages of acupuncture. This article provides a new insight into the scientific application of the combination of acupuncture and medicines.
哮喘针药结合针灸转化医学药源性疾病数据挖掘临床优势选穴规律
asthmacombination of acupuncture and medicinesacupuncture and moxibustiontranslational medicineiatrogenic diseasesdata miningclinical advantagespoint selection rules
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