Objective,2,To observe the clinical efficacy of Modified Qilong Quyu Mixture plus external treatment and conditioning in the treatment of lower limb venous ulcer of qi deficiency and blood stasis syndrome.,Methods,2,One hundred patients with lower limb venous ulcer of qi deficiency and blood stasis syndrome were randomly divided into treatment group （,n,=50） and control group （,n,=50）. Patients in the control group were given external treatment and conditioning plus oral administration of Maixuekang Capsules， and patients in the treatment group were given external treatment and conditioning plus oral administration of Modified Qilong Quyu Mixture. The course of treatment in both groups was 8 weeks. The clinical efficacy was observed， and the changes in trauma area， topical traditional Chinese medicine （TCM） syndrome score and the visual analogue scale （VAS） score of pain were compared between the two groups before and after treatment.,Results,2,①During the trial， 4 cases dropped or got removed from the treatment group， and 5 cases dropped or got removed from the control group. Finally， 46 cases in the treatment group and 45 cases in the control group completed the trial. ②The total effective rate of the treatment group and control group was 76.1% and 66.7%， respectively， and the clinical efficacy of the treatment group was better than that of the control group （,P,<,0.05）. ③After treatment， the trauma area of patients became smaller in both groups （,P,<,0.05）； and the trauma area of patients in the treatment group was smaller than that in the control group （,P,<,0.05）. ④After treatment， the score in the items including peritraumatic pigmentation， lack of new epithelial cells， exudation， dull or dark purple granulation tissue， pus decay and peritraumatic swelling and the total score of topical TCM syndrome decreased in the treatment group （,P,<,0.05）， while in the control group only the score in exudation， dull or dark purple granulation tissue and peritraumatic swelling decreased （,P,<,0.05）； After treatment， the score in the items of peritraumatic pigmentation， lack of new epithelial cells， exudation and dull or dark purple granulation tissue， and the total score of topical TCM syndrome in the treatment group were lower than those in the control group （,P,<,0.05）. ⑤The pain VAS score decreased in both groups after treatment （,P,<,0.05）； After treatment， the pain VAS score was lower in the treatment group than that in the control group （,P,<,0.05）.,Conclusion,2,Modified Qilong Quyu Mixture plus external treatment and conditioning has achieved a satisfactory therapeutic result in treating lower limb venous ulcer of qi deficiency and blood stasis syndrome since the combined therapy can effectively improve the topical traumatic symptoms， alleviate pain and promote wound healing.