The clinical experience of Professor Yang Shuo’s “spirit-regulating acupuncture” for the treatment of emotional diseases is introduced. Professor Yang believes that the key to regulating the spirit lies in the qi and blood of the internal organs and in the abundance of yang qi. The main acupuncture points selected are five-zang back-shu points and five-zhi points together with Jiaji points.Given the difference between short-term onset and long-term onset of emotional diseases， shallow needling of back-shu points and five-zhi points or deep needling of Jiaji points should be emphasized accordingly during treatment.When applying shallow needling to the back-shu points and five-zhi points on the left side， the needle tip points to the head； when applying shallow needling to the back-shu points and five-zhi points on the right side， the needle tip points to the foot.Through the application of “spirit-regulating acupuncture”， the purpose of warming yang and nourishing spirit， coordinated regulation of spirit， five internal organs and qi movement can be realizen. One proven case is exemplified.