Objective,2,To observe the clinical effect of fistulotomy combined with marsupialization on the treatment of low anal fistula.,Methods,2,Eighty patients with low anal fistula were randomly divided into a treatment group （,n,=40） and a control group （,n,=40）. The control group was treated with fistulotomy alone， and the treatment group was treated with fistulotomy and marsupialization. The clinical effect was observed， the duration of surgery， the area of surgical wound， the visual analogue scale （VAS） score of postoperative pain， the amount of postoperative wound exudation， the time taken for wound healing， the scar area at healing， and the Wexner score of postoperative anal incontinence were compared between the two groups.,Results,2,①After treatment， patients in both groups were cured clinically， and there was no statistically significant difference in the clinical effect between the two groups （,P,>,0.05）. ②The treatment group took longer time to operate than the control group， the average pain VAS score of the treatment group was lower than that of the control group， the average amount of wound exudation of the treatment group was less than that of the control group， and these differences were statistically significant （,P,<,0.05）. ③The surgical wound area and scar area at healing in the treatment group were smaller than those in the control group， the time taken for wound healing was shorter than that in the control group， and these differences were statistically significant （,P,<,0.05）. ④The difference in the Wexner score of postoperative anal incontinence between the two groups was not statistically significant （,P,>,0.05）.,Conclusion,2,Fistulotomy combined with marsupialization can effectively and safely treat low anal fistulas with a shorter treatment course and milder postoperative complications than fistulotomy alone， without increasing the risk of anal incontinence.