Objective,2,To observe the clinical efficacy of treating-winter-diseases-in -summer combined with doxazosin mesylate tablets in the treatment of benign prostatic hyperplasia（BPH）.,Methods,2,A total of 108 patients with BPH were randomly divided into two groups， the treatment group and the control group， 54 cases in each group. The control group received doxazosin mesylate tablets， while the treatment group received doxazosin mesylate tablets combined with treating-winter-diseases-in-summer（moxibustion and acupoint application in the dog days）. The treatment course of both groups was in the dog days（about 6 weeks in summer）of 2018， 2019 and 2020 . The changes of international prostate symptom score （IPSS）， quality of life score （QOL）， TCM syndrome score， maximum urine flow rate （Q,max,）， and prostate volume （PV） in two groups were observed before and after treatment. IPSS， QOL， and TCM syndrome scores were followed up in the winter of the same year.,Results,2,①A total of 98 patients completed the treatment， including 50 cases in the treatment group and 48 cases in the control group. ②The total effective rate was 72.00% in the treatment group and 56.35% in the control group. The clinical efficacy of the treatment group was better than that of the control group （,P,<,0.05）. ③After treatment， IPSS， QOL， TCM syndrome score， and Q,max, in two groups were significantly improved compared with before treatment （,P,<,0.05）. The treatment group was better than the control group in improving QOL， TCM syndrome score， and Q,max, （,P,<,0.05）. ④During the period of follow up， IPSS， QOL， and TCM syndrome scores of the two groups were significantly improved compared with those before treatment （,P,<,0.05）， QOL and TCM syndrome scores were significantly improved compared with those after treatment （,P,<,0.05）； There was no significant difference in IPSS between follow-up and after treatment in the treatment group（,P,>,0.05）， while there was a significant difference in IPSS between follow-up and after treatment in the control group （,P,<,0.05）； The improvement of IPSS， QOL， and TCM syndrome score in the treatment group was better than that in the control group （,P,<,0.05）. ⑤There was no significant difference in the incidence of adverse reactions between the two groups （,P,>,0.05）.,Conclusions,2,Treating-winter-diseases-in -summer combined with doxazosin mesylate tablets in the treatment of BPH can improve clinical efficacy， reduce IPSS， improve the urination symptoms， and improve the quality of life of patients. The treatment is safe and lasting for a while.