LU Zonglin,YANG Yanhong,FAN Zeng,et al.Treatment of male infertility with sperm DNA damage based on turbid pathogen pathogenesis[J].Shanghai Journal of Traditional Chinese Medicine,2022,56(11):33-37.
LU Zonglin,YANG Yanhong,FAN Zeng,et al.Treatment of male infertility with sperm DNA damage based on turbid pathogen pathogenesis[J].Shanghai Journal of Traditional Chinese Medicine,2022,56(11):33-37. DOI: 10.16305/j.1007-1334.2022.2101125.
Sperm DNA damage is closely related to male infertility. According to the etiological analysis and syndrome differentiation, infection, tendon tumor (varicocele), obesity and old age can trigger the production of turbid pathogen inside the body. Turbid pathogen may be an important pathological product bridging the high-risk cause of sperm DNA damage and sperm nucleus damage. Microscopic differentiation reveals that the turbid pathogen is the core pathogenesis of sperm nucleus damage. Huazhuo (turbidity-resolving) method of traditional Chinese medicine is an important measure to block sperm nucleus damage and prevent male infertility due to sperm DNA damage. A proven case is provided for exemplification.
关键词
男性不育浊邪精子DNA损伤中医药疗法
Keywords
male infertilityturbid pathogensperm DNA damagetraditional Chinese medicine therapy
references
SHAMSI M B, KUMAR R, DADA R. Evaluation of nuclear DNA damage in human spermatozoa in men opting for assisted reproduction[J]. Indian J Med Res, 2008, 127(2): 115-123.