This paper introduces the clinical experience of applying Guizhi Fuling Pill combined with other prescriptions in the treatment of miscellaneous diseases. They are the cases of frequent micturition treated with Guizhi Fuling Pill and Sini San， the cases of unhealing ulcer of dorsum of foot treated with Guizhi Fuling Pill and Siwei Jianbu Decoction， the cases of lip numbness treated with Guizhi Fuling Pill and Dachaihu Decoction， the cases of ardor urinae treated with Guizhi Fuling Pill and Zhuling Decoction and the cases of feverish sensation over the palm and sole treated with Guizhi Fuling Pill and Sanwu Huangqin Decoction. It is considered that the differentiation and treatment of the diseases should be combined with constitution of the patients and by the method of correspondence between prescriptions and syndromes.