Objective,2,To explore the clinical efficacy of acupuncture and medicine combined with enhanced recovery after surgery (ERAS) on promoting the rehabilitation of patients undergoing laparoscopic colorectal cancer surgery.,Methods,2,One hundred and twenty patients underwent laparoscopic colorectal radical resection of colorectal cancer between January 2019 and August 2020 were randomly divided into the acupuncture and medicine (AM) group (62 cases) and the traditional treatment (TT) group (58 cases). The patients in the TT group were treated only with ERAS, while the patients in the AM group were treated additionally with electroacupuncture at Zusanli point after 6 hours of operation, and Rensheng Yiyi Fuzi Baijiang Powder after 12 hours of operation, with a course of 3 days. Compare the first aerofluxus time, first defecation time, oral feeding time, score of Chinese medical syndrome, level of prealbumin and albumin, postoperative complications, hospital stay and hospitalization expenses between two groups.,Results,2,The first aerofluxus time, first defecation time and oral feeding time of the AM group were significantly shorter than those of the TT group (,P,<,0.05). The score of Chinese medical syndrome of the AM group was lower than that of the TT group (,P,<,0.01). The level of prealbumin and albumin was the same between the two groups before operation and on the first postoperative day(,P,>,0.05), however, they were higher in the AM group on the fifth postoperative day(,P,<,0.05). The total postoperative complications, hospital stay and hospitalization expenses of the AM group were less than those of the TT group (,P,<,0.05).,Conclusion,2,Acupuncture and medicine combined with ERAS can accelerate the recovery of gastrointestinal function, improve nutritional status, decrease postoperative complications, shorten hospital stay and save hospitalization expenses for patients who undergo laparoscopic surgery for colorectal cancer.