益气聪明汤联合西药治疗气血亏虚型恢复期后循环缺血性眩晕的临床研究
Clinical observation on Yiqi Congming Decoction combined with western medicine in treating posterior circulation ischemic vertigo of qi and blood deficiency syndrome in recovery period
- 上海中医药杂志 2021年55卷第4期 页码：60-62,91
- 作者机构：
1.上海市普陀区中医医院脑病科（上海 200062）
- 作者简介：
亓光峰，男，硕士，副主任医师，主要从事中西医结合防治心脑血管病的临床与研究工作
- 基金信息：上海市卫计委进一步加快中医药事业发展三年行动计划项目(ZY3-JSFC-1-1013)
DOI：10.16305/j.1007-1334.2021.2009091
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亓光峰, 赵超蓉. 益气聪明汤联合西药治疗气血亏虚型恢复期后循环缺血性眩晕的临床研究[J]. 上海中医药杂志, 2021,55(4):60-62,91.
Guangfeng QI, Chaorong ZHAO. Clinical observation on Yiqi Congming Decoction combined with western medicine in treating posterior circulation ischemic vertigo of qi and blood deficiency syndrome in recovery period[J]. Shanghai Journal of Traditional Chinese Medicine, 2021,55(4):60-62,91.
亓光峰, 赵超蓉. 益气聪明汤联合西药治疗气血亏虚型恢复期后循环缺血性眩晕的临床研究[J]. 上海中医药杂志, 2021,55(4):60-62,91. DOI： 10.16305/j.1007-1334.2021.2009091.
Guangfeng QI, Chaorong ZHAO. Clinical observation on Yiqi Congming Decoction combined with western medicine in treating posterior circulation ischemic vertigo of qi and blood deficiency syndrome in recovery period[J]. Shanghai Journal of Traditional Chinese Medicine, 2021,55(4):60-62,91. DOI： 10.16305/j.1007-1334.2021.2009091.
摘要
目的,2,观察益气聪明汤联合西药治疗气血亏虚型恢复期后循环缺血性眩晕的临床疗效。,方法,2,将110例气血亏虚型恢复期后循环缺血性眩晕患者随机分为治疗组和对照组，每组55例。对照组予阿司匹林和盐酸氟桂利嗪治疗，治疗组在对照组治疗措施基础上加用益气聪明汤。两组疗程均为28 d，观察临床疗效，比较中医证候积分、经颅多普勒超声脑血流指标的变化情况，同时进行安全性评价。,结果,2,①治疗组、对照组的愈显率分别为94.5%、50.9%，治疗组临床疗效优于对照组（,P,<,0.01）。②治疗前后组内比较，两组中医证候积分均降低（,P,<,0.01）；组间治疗后比较，治疗组中医证候积分低于对照组（,P,<,0.01）。③治疗前后组内比较，两组左椎动脉、右椎动脉、基底动脉的平均血流速度和搏动指数差异有统计学意义（,P,<,0.01）；组间治疗后比较，上述指标差异均有统计学意义（,P,<,0.05）。④治疗组、对照组的不良反应发生率分别为16.3%、18.2%，差异无统计学意义（,P,>,0.05）。,结论,2,与单纯采用西药相比，加用益气聪明汤治疗气血亏虚型恢复期后循环缺血性眩晕疗效满意，能更好地改善患者的临床症状，其作用机制可能与增加椎-基底动脉系统的血液灌注有关。
Abstract
Objective,2,To observe the clinical effect of Yiqi Congming Decoction combined with western medicine on posterior circulation ischemic vertigo (PCIV) of qi and blood deficiency syndrome in recovery period.,Methods,2,A total of 110 PCIV cases of qi and blood deficiency syndrome in recovery period were randomly divided into treatment group (,n,=55) and control group (,n,=55). The control group was administered with aspirin and flunarizine hydrochloride, while the treatment group was administered with Yiqi Congming Decoction besides the conventional treatment of the control group. The course of treatment in both groups was 28 days. The clinical effect was observed, the changes of TCM syndrome scores and transcranial Doppler ultrasound (TCDU) cerebral blood flow indexes (CBFI) were compared, and the safety was evaluated simultaneously.,Result,2,①The cured and markedly effective rate of the treatment group and the control group were 94.5% and 50.9%, respectively. The clinical effect of the treatment group was better than that of the control group (,P,<,0.01). ②The TCM symptom scores in both groups decreased after treatment (,P,<,0.01); The TCM syndrome score in the treatment group was lower than that in the control group after treatment (,P,<,0.01). ③The mean blood flow velocity and pulsatility index of left vertebral artery, right vertebral artery and basilar artery in the two groups were significantly different before and after treatment (,P,<,0.01). After treatment, the above indexes were significantly different between the groups (,P,<,0.05). ④The incidence of adverse reactions in the treatment group and the control group were 16.3% and 18.2% respectively, with no significant difference (,P,>,0.05).,Conclusion,2,Compared with the single use of western medicine, the combined use of Yiqi Congming Decoction with western medicine has more satisfactory curative effect on PCIV of qi and blood deficiency syndrome in recovery period, and can better improve patients’ clinical symptoms. The mechanism of action may be related to increasing hemoperfusion of vertebrobasilar artery system.
关键词
后循环缺血眩晕恢复期益气聪明汤气血亏虚
Keywords
posterior circulation ischemiavertigorecovery periodYiqi Congming Decoctionqi and blood deficiency
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