
1.上海中医药大学附属岳阳中西医结合医院(上海 200437)
2.上海市奉贤区中医医院(上海 201499)
何聪,男,硕士研究生,主要从事中西医结合防治消化系统疾病的临床研究工作
周秉舵,副主任医师,硕士研究生导师;E-mail:bingduozhou@163.com
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何聪, 王慧超, 周秉舵, 等. 清化和中方加减治疗脾胃湿热型慢性非萎缩性胃炎的临床疗效观察[J]. 上海中医药杂志, 2021,55(2):56-58,62.
Cong HE, Huichao WANG, Bingduo ZHOU, et al. Clinical efficacy of modified Qinghua Hezhong Decoction on chronic non-atrophic gastritis with spleen and stomach damp-heat syndrome[J]. Shanghai Journal of Traditional Chinese Medicine, 2021,55(2):56-58,62.
何聪, 王慧超, 周秉舵, 等. 清化和中方加减治疗脾胃湿热型慢性非萎缩性胃炎的临床疗效观察[J]. 上海中医药杂志, 2021,55(2):56-58,62. DOI: 10.16305/j.1007-1334.2021.2009006.
Cong HE, Huichao WANG, Bingduo ZHOU, et al. Clinical efficacy of modified Qinghua Hezhong Decoction on chronic non-atrophic gastritis with spleen and stomach damp-heat syndrome[J]. Shanghai Journal of Traditional Chinese Medicine, 2021,55(2):56-58,62. DOI: 10.16305/j.1007-1334.2021.2009006.
目的,2,观察清化和中方加减治疗脾胃湿热型慢性非萎缩性胃炎的临床疗效。,方法,2,将82例慢性非萎缩性胃炎患者随机分为治疗组和对照组,每组41例。治疗组予清化和中方加减,对照组予雷贝拉唑钠肠溶胶囊。两组均连续服药28 d,观察临床疗效以及中医证候积分、胃镜疗效、病理疗效等情况。,结果,2,①治疗组、对照组总有效率分别为92.68%、73.17%(,P,<,0.05),治疗组临床疗效优于对照组(,P,<,0.05)。②治疗前后组内比较,两组中医脾胃湿热证候积分差异均有统计学意义(,P,<,0.05);组间治疗后比较,治疗组积分显著低于对照组(,P,<,0.05)。③组间治疗后比较,治疗组胃镜疗效和病理疗效均优于对照组(,P,<,0.05)。,结论,2,清化和中方治疗脾胃湿热型慢性非萎缩性胃炎,安全有效。
Objective,2,To observe the clinical effect of modified Qinghua Hezhong(QHHZ) Decoction in the treatment of chronic non-atrophic gastritis (CNAG) with spleen and stomach damp-heat (SSDH) syndrome.,Methods,2,A total of 82 patients with CNAG were randomly divided into treatment group and control group with 41 cases in each group. Patients in the treatment group were treated with modified QHHZ Decoction, while patients in the control group were treated with Rabeprazole Sodium Enteric Coated Capsules. All patients received 4 weeks of treatment. The changes of clinical efficacy, TCM syndrome scores, gastroscopy scores and pathological test scores were observed before and after treatment.,Results,2,①The total effective rate of the treatment group was 92.68%, while that of the control group was 73.17% (,P,<,0.05). The curative effect of the treatment group was better than that of the control group (,P,<,0.05). ②The TCM syndrome scores of spleen and stomach damp-heat syndrome in the two groups were lower than those before treatment respectively, and the differences were statistically significant (,P,<,0.05). After treatment, the TCM syndrome scores of the treatment group was significantly lower than the scores of the control group (,P,<,0.05). ③After treatment, the scores of gastroscopy and pathological test of the treatment group were higher than those of the control group (,P,<,0.05).,Conclusion,2,Qinghua Hezhong Decoction is safe and effective in treating chronic non-atrophic gastritis with spleen and stomach damp-heat syndrome.
慢性非萎缩性胃炎脾胃湿热证清化和中方临床试验
chronic non-atrophic gastritisspleen and stomach damp-heat syndromeQinghua Hezhong Decoctionclinical trial
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