This paper introduces professor Chen Xiangjun’s experience in treating scleroderma,and holds that the key to the pathogenesis of scleroderma is “kidney deficiency and blood stasis”. The main treatment is to warm the kidney and disperse cold. If there is deficiency of nourishing blood,nourishing the kidney and nourishing the blood is the main treatment,no matter warming or nourishing yin,it is the pathological key to qi deficiency and blood stasis. Therefore,replenishing qi and activating blood is used through all the time.