This article reviews the current distribution of TCM syndromes in Alzheimer’s disease(AD),and summarizes and discusses the standardization of diagnostic criteria for TCM syndromes in AD. The clinical manifestations of AD are mostly complex syndromes of deficient syndrome with excessive symptoms.Deficient syndrome may include kidney deficiency,heart deficiency,etc.Excessive syndrome may include phlegm turbidity,blood stasis, etc. At present,based on standardized TCM syndrome factors,the AD syndrome scale with TCM characteristics has been used in the clinic.The biological research progress of AD can provide scientific basis for microscopic differentiation of TCM syndromes,and provide research strategies for interpreting AD TCM syndrome theory.The biological research of AD will help the organic combination of macro-syndrome and micro-syndrome differentiation,and formulate the diagnostic criteria of syndromes that are compatible with the entire pathological development of AD.