Programmed death receptor-1(PD-1) has been one of the frontier hotspots in tumor therapy in recent years. PD-1 inhibitors are often used in combination with various tumor therapies clinically, but there are still many patients who do not respond to the treatment or whose tumors recur due to drug resistance after treatment, or whose toxic and side effects are too strong to complete the treatment. Therefore, their compliance and quality of life are significantly reduced. Professor Xu Zhenye believes that the intervention of traditional Chinese medicine in patients during the course of PD-1/PD-L1 inhibitor treatment can effectively reduce the toxic and side effects of immunotherapy, help patients complete the course of immunotherapy, and may have the effect of enhancing the efficacy of immunotherapy. Two proved cases are attached.