Objective:To explore the effect of acupuncture method of strengthing spleen and invigorating kidney on ovulation and endometrial receptivity of infertile patients with PCOS undergoing in vitro fertilization(IVF)-embryo transfer(ET). MethodsEighty-two infertile patients with PCOS who undergoing IVF-ET were selected and randomly divided into the control group(42 cases)and the treatment group(40 cases). All the patients were treated with western medicine antagonist ovulation regimen,and the patients in the treatment group were treated with the acupuncture method of strengthing spleen and invigorating kidney based on obove. The number of retrieved oocytes and oosperms and the rate of high-quality embryos were compared. The levels of luteinizing hormone(LH),estradiol(E,2,)and progesterone(P)on the day of human chorionic gonadotropin(HCG)injection were detected and compared. The endometrial thickness and blood flow were tested on the day of HCG injection. The dosage of gonadotropin(Gn)in the cycle,the number of fresh embryo transfer,the HCG positive rate and the clinical pregnancy rate were compared.  Results:①There were no statistically significant differences on the number of retrieved oocytes and oosperms between the two groups(P,>,0.05). The rate of high-quality embryos in the treatment group was higher than that in the control group(P,<,0.05). ②The levels of E,2, and P on the day of HCG injection in the treatment group were higher than those in the control group(P,<,0.05). ③There was no statistically significant difference on the endometrial thickness on the day of HCG injection between the two groups(P,>,0.05). The endometrial blood flow positive distribution in the treatment group was superior to the control group(P,<,0.05). ④In the course of treatment,the dosage of Gn in the treatment group was less than that in the control group(P,<,0.05). ⑤There were no statistically 〖JP+significant differences on the HCG positive rate and the clinical pregnancy rate between the two groups(P,>,0.05).  Conclusion:The acupuncture method of strengthing spleen and invigorating kidney combined with western medicine antagonist ovulation regimen can improve the endometrial receptivity and sex hormone levels,enhance the high-quality embryos rate,and reduce the dosage of Gn in infertile patients with PCOS undergoing IVF-ET.