Changes of skeletal muscle function and structure in patients with chronic obstructive pulmonary disease and effects of traditional Chinese medical exercise intervention
XIAO Lu, LI Peijun, DUAN Hongxia, et al. Changes of skeletal muscle function and structure in patients with chronic obstructive pulmonary disease and effects of traditional Chinese medical exercise intervention[J]. Shanghai Journal of Traditional Chinese Medicine, 2020,54(7):99-105.
XIAO Lu, LI Peijun, DUAN Hongxia, et al. Changes of skeletal muscle function and structure in patients with chronic obstructive pulmonary disease and effects of traditional Chinese medical exercise intervention[J]. Shanghai Journal of Traditional Chinese Medicine, 2020,54(7):99-105. DOI: 10.16305/j.1007-1334.2020.07.015.
Skeletal muscle dysfunction is a prominent manifestation of extrapulmonary effect of chronic obstructive pulmonary disease (COPD). Due to the low physical activity level, systemic inflammation, hypoxia and other reasons, changes in structural and metabolic characteristics that occur in the early stage of the disease, including skeletal muscle mass reduction, cross-sectional muscle area decrease, reduction of total muscle fiber amount, muscle fiber-type shifting, capillary density decrease, mitochondrial dysfunction, etc., may cause weakening of skeletal muscle strength and endurance of patients, affect their exercise performance, increase hospitalization rate and mortality rate, and seriously affect their quality of life. As a unique form of exercise in China, traditional Chinese medical exercise (Gongfa) belongs to the low and moderate intensity aerobic exercise and is an effective exercise rehabilitation method as it can effectively slow down and improve the structural changes of skeletal muscle, improve its muscle strength and enhance its muscle endurance by reducing the level of inflammatory factors and improving blood oxygen level in COPD patients.
关键词
慢性阻塞性肺疾病骨骼肌功能障碍中医传统功法运动康复肺康复
Keywords
chronic obstructive pulmonary diseaseskeletal muscledysfunctiontraditional Chinese medicinetraditional Chinese medical exerciseexercise rehabilitationlung rehabilitation