Professor Que Huafa’s experience in the treatment of thyroid cancer was introduced. It was suggested that the pathogenesis of the disease was due to the deficiency of vital energy and the stagnation of toxin,he emphasized that the treatments of this disease were based on the strengthening of vital energy and removing pathogenic factors. It was necessary to review for differentiation and regulating the spleen and kidney. Not only combination of disease and syndrome but also differentiation of meridians should be concerned. He was expert in using the drugs to guide the meridians. He paid more attentions to the constitution differentiation, and advocated strengthening yang qi.One proven case was presented.