The clinical foundation of traditional Chinese medicine (TCM) was laid in the process of dealing with febrile diseases (epidemic diseases). The opposition between Wenyi (febrile contagious diseases) and Shanghan (cold-evil induced diseases) in history was to explore more effective clinical treatment methods. Although the diagnosis and treatment of epidemic diseases are special, the principles and rules of the six-channel pattern identification and treatment are still the basics. Mastering the methods of the six-channel pattern identification and corresponding treatment is helpful for the understanding and application of TCM diagnosis and treatment program for coronavirus disease 2019 (COVID-19).