PI3K-AKT信号通路与抑郁症的关系及中医干预作用研究进展

黄芸; 张治楠; 黄泳; 曲姗姗; 钟正

doi:10.16305/j.1007-1334.2020.02.024

您当前的位置：

首页 >

文章列表页 >

PI3K-AKT信号通路与抑郁症的关系及中医干预作用研究进展

综述 | 更新时间：2022-08-31

- PI3K-AKT信号通路与抑郁症的关系及中医干预作用研究进展
- Research progress on Chinese traditional medicine in the treatment of depression via PI3K-AKT signaling pathway The relationship between PI3K-AKT signaling pathway and depression and the research progress on TCM intervention 
- 上海中医药杂志 2020年54卷第2期页码：108-112
- 作者机构：
  
  1. 南方医科大学第一临床医学院,广东,广州,510515
  2. 南方医科大学中医药学院,广东,广州,510515
  3. 南方医科大学南方医院中医科,广东,广州,510515
- 作者简介：
- 基金信息：
  
  国家自然科学基金项目(81873359,81603474);广东省科学技术厅自然科学基金项目(2016A030313522,2016A030310383);广东省科学技术厅科技计划项目(2013A032500001);广东省广州市科技创新委员会科技计划项目(201707010041);广东省中医药局第二批中医临床优秀人才研修项目;南方医院2018年度院长基金项目(2018Z023)
- DOI：10.16305/j.1007-1334.2020.02.024
  中图分类号：
扫描看全文
黄芸, 张治楠, 黄泳, 等. PI3K-AKT信号通路与抑郁症的关系及中医干预作用研究进展[J]. 上海中医药杂志, 2020,54(2):108-112.

HUANG Yun, ZHANG Zhinan, HUANG Yong, et al. Research progress on Chinese traditional medicine in the treatment of depression via PI3K-AKT signaling pathway The relationship between PI3K-AKT signaling pathway and depression and the research progress on TCM intervention [J]. Shanghai Journal of Traditional Chinese Medicine, 2020,54(2):108-112.
黄芸, 张治楠, 黄泳, 等. PI3K-AKT信号通路与抑郁症的关系及中医干预作用研究进展[J]. 上海中医药杂志, 2020,54(2):108-112. DOI： 10.16305/j.1007-1334.2020.02.024.

HUANG Yun, ZHANG Zhinan, HUANG Yong, et al. Research progress on Chinese traditional medicine in the treatment of depression via PI3K-AKT signaling pathway The relationship between PI3K-AKT signaling pathway and depression and the research progress on TCM intervention [J]. Shanghai Journal of Traditional Chinese Medicine, 2020,54(2):108-112. DOI： 10.16305/j.1007-1334.2020.02.024.

摘要

综述PI3K-AKT信号通路与抑郁症的关系及中医干预作用研究进展。研究发现,抑郁症的发病机制与PI3K-AKT信号通路密切相关,通过促进PI3K-AKT信号通路激活,能够改善突触可塑性,进而对抑郁行为的改善起促进作用。针灸、中药、方剂对抑郁症有一定的疗效,通过促进PI3K-AKT激活改善突触可塑性是其改善抑郁状态的作用机制之一。

Abstract

The research progress on the relationship between PI3K-AKT signaling pathway and the research progress on depression and the effect of TCM intervention was reviewed. It was found that the pathogenesis of depression is closely related to PI3K-AKT signaling pathway. By promoting the activation of PI3K-AKT signaling pathway, synaptic plasticity can be improved to facilitate the improvement of depression behaviors. Acupuncture, traditional Chinese medicine and formulas have a certain effect on the treatment of depression with the mechanism of improving synaptic plasticity via the activation of PI3K-Akt signaling pathway.

关键词

抑郁症PI3K-AKT突触可塑性针灸中药方剂综述

Keywords

depressionPI3K-AKTsynaptic plasticityacupuncturetraditional Chinese medicineformulasreview

references

浏览量

1524

下载量

CSCD

CNKI被引量

文章被引用时，请邮件提醒。

提交

工具集

关联资源

毛发再生过程中诱导毛囊干细胞激活因素的研究进展

中医药对慢性乙型肝炎免疫调节作用概述

腰椎间盘突出症非药物保守治疗的研究进展

经皮穴位电刺激在外科手术中的临床应用进展

中药蚕茧壳的药理及临床研究进展