This paper introduces Professor Lin Xingdong’s experience in clinical application of Wumei pills. It is considered that Wumei pill is effective in the treatment of nervous system diseases with the patterns of deficiency of liver yin and yang, internal stirring of liver-wind and mixture of cold and heat. The connotation of Jueyin disease, the elucidation of Wumei pill and the characteristics of correspondence between prescription and syndrome are analyzed. At the same time, This paper also points out some notes in the application of Wumei pills. And four proven cases are presented.