LI Xilin, LIU Guobin, XIA Jing, et al. Determination of total mercury in zizhu ointment by atomic absorption spectrophotometry [J]. Shanghai Journal of Traditional Chinese Medicine, 2019,53(10):97-99.
LI Xilin, LIU Guobin, XIA Jing, et al. Determination of total mercury in zizhu ointment by atomic absorption spectrophotometry [J]. Shanghai Journal of Traditional Chinese Medicine, 2019,53(10):97-99. DOI: 10.16305/j.1007-1334.2019.10.022.
Objective:To study the content determination of total mercury in Zizhu Ointment and facilitate the establishment of effective quality control methods. MethodsAfter microwave digestion of samples, the content of total mercury in Zizhu Ointment was determined by atomic absorption spectrophotometry (AAS). Results:The linear relationship of the established method was y=0.001 8x+0.000 3, the correlation coefficient was 0.999 9, and the recovery rate was 92.02%-105.84%. The average content of total mercury in Zizhu Ointment was 3.13% with RSD of 2.70%. Conclusion:This method provides a practical and reliable basis for formulation of the quality standards of Zizhu Ointment.