YU Yunxia, XIA Jiawen, XIONG Youxiang. Research progress in reversal of multidrug resistance in liver cancer by traditional Chinese medicine[J]. Shanghai Journal of Traditional Chinese Medicine, 2019,53(8):92-97.
YU Yunxia, XIA Jiawen, XIONG Youxiang. Research progress in reversal of multidrug resistance in liver cancer by traditional Chinese medicine[J]. Shanghai Journal of Traditional Chinese Medicine, 2019,53(8):92-97. DOI: 10.16305/j.1007-1334.2019.08.022.
Considering relevant studies on reversal of multidrug resistance in liver cancer in recent 10 years both at home and abroad, this paper summarizes the reversal effect of traditional Chinese medicine in liver cancer in inhibiting membrane transporter, inhibiting multidrug resistance (MDR) genes, inhibiting the anti-apoptotic pathway, reversing enzyme-mediated MDR and improving the microenvironment of tumor cells, and also summarizes the existing problems in and the direction of research, so as to provide new ideas for clinical treatment.
关键词
中药肝癌多药耐药逆转机制综述
Keywords
traditional Chinese medicineliver cancermultidrug resistancereversalmechanismreview