CAI Yiqing, CHEN Yu, ZHANG Teng. Research progress in vascular remodeling mechanisms and prevention and treatment of hypertension with traditional Chinese medicine[J]. Shanghai Journal of Traditional Chinese Medicine, 2019,53(7):88-92.
CAI Yiqing, CHEN Yu, ZHANG Teng. Research progress in vascular remodeling mechanisms and prevention and treatment of hypertension with traditional Chinese medicine[J]. Shanghai Journal of Traditional Chinese Medicine, 2019,53(7):88-92. DOI: 10.16305/j.1007-1334.2019.07.021.
This paper summarizes the major mechanisms underlying vascular remodeling and the interventional effects of traditional Chinese medicine in hypertension. Vascular remodeling is an important pathological link in damages to the target organs by hypertension. Abnormal hemodynamics, vasoactive substances, extracellular matrix, non-coding RNAs and other mechanisms can lead to vascular remodeling. Compound formulas of Chinese medicines (e.g., Qingxuan Jiangya Decoction and Simiao Yongan Decoction) and Chinese herbal extracts (e.g., vaccarin and puerarin) play a positive role in hypertensive vascular remodeling.
关键词
高血压血管重构中医药疗法综述
Keywords
hypertensionvascular remodelingtherapy in traditional Chinese medicinereview