ZHANG Chunyan, ZHANG Bingbing, LU Jianrao, et al. Optimizing extraction process of Ningshen Granule by comprehensive evaluation of multiple mark[J]. Shanghai Journal of Traditional Chinese Medicine, 2019,53(1):96-100.
ZHANG Chunyan, ZHANG Bingbing, LU Jianrao, et al. Optimizing extraction process of Ningshen Granule by comprehensive evaluation of multiple mark[J]. Shanghai Journal of Traditional Chinese Medicine, 2019,53(1):96-100. DOI: 10.16305/j.1007-1334.2019.01.024.
Objective:To investigate the extraction process of Ningshen Granules. MethodsOrthogonal test was used to investigate the effects of solid-liquid ratio,extraction time,and times on extraction process. The extraction process was optimized by comprehensive evaluation indexes based on the content of 2,3,5,4′-tetrahydroxy stilbene-2-O-β-D-glucoside,naringin,salvianolic acid B,and the extraction yield. Results:According to the result of comprehensive score,the optimal extraction conditions of this preparation were as follows:extracted three times with 8 times of water quantity,each for 0.5 h. Conclusion:This optimized process is simple,feasible,repeatable.
关键词
宁神颗粒正交试验二苯乙烯苷柚皮苷丹酚酸B综合加权
Keywords
Ningshen Granuleorthogonal experiment2354′-tetrahydroxy stilbene-2-O-β-D-glucosidenaringinsalvianolic acid Bcomprehensive evaluation of multiple mark