1. 上海市奉贤区中医医院急诊科,上海,201499
扫 描 看 全 文
董进军, 晋玉梅, 祖建国. 特色中药内外合治对老年气阴两虚兼血瘀湿阻型慢性心力衰竭影响的临床研究[J]. 上海中医药杂志, 2019,53(1):52-54.
DONG Jinjun, JIN Yumei, ZU Jianguo. Clinical study of internal and external treatment of traditional Chinese medicine for chronic heart failure in aged patients with qi-yin deficiency,blood stasis and damp obstruction[J]. Shanghai Journal of Traditional Chinese Medicine, 2019,53(1):52-54.
董进军, 晋玉梅, 祖建国. 特色中药内外合治对老年气阴两虚兼血瘀湿阻型慢性心力衰竭影响的临床研究[J]. 上海中医药杂志, 2019,53(1):52-54. DOI: 10.16305/j.1007-1334.2019.01.014.
DONG Jinjun, JIN Yumei, ZU Jianguo. Clinical study of internal and external treatment of traditional Chinese medicine for chronic heart failure in aged patients with qi-yin deficiency,blood stasis and damp obstruction[J]. Shanghai Journal of Traditional Chinese Medicine, 2019,53(1):52-54. DOI: 10.16305/j.1007-1334.2019.01.014.
目的:观察特色中药内外合治法联合常规西药治疗气阴两虚兼血瘀湿阻型老年慢性心力衰竭(CHF)的临床疗效。 方法:将136例气阴两虚兼血瘀湿阻型老年CHF患者随机分成治疗组与对照组,每组68例。对照组予常规西药治疗,治疗组在对照组治疗措施基础上加予强心Ⅱ号汤口服、足浴及二乌温阳贴穴位敷贴。两组疗程均为2个月,观察临床疗效及用药不良反应情况,比较心功能指标、6 min步行距离及血清B型钠尿肽(BNP)、C反应蛋白(CRP)及心肌肌钙蛋白I(cTnI)水平的变化情况。 结果:①最终完成试验者124例,治疗组62例,对照组62例。②治疗组、对照组总有效率分别为91.94%、75.81%;组间临床疗效比较,治疗组明显优于对照组(P<0.05)。③组间治疗后比较,治疗组LVEF明显高于对照组,而LVEDD、LVESD明显低于对照组(P<0.05)。④组间治疗后比较,治疗组6 min步行距离明显多于对照组(P<0.05)。⑤组间治疗后比较,治疗组BNP、CRP及cTnI水平明显低于对照组(P<0.05)。⑥组间不良反应发生率比较,差异无统计学意义(P>0.05)。 结论:特色中药内外合治法联合常规西药治疗气阴两虚兼血瘀湿阻型老年CHF,可显著提高临床疗效及患者的运动耐量,改善其心功能,降低血清BNP、CRP及cTnI水平,且安全性较好。
Objective:To observe the clinical effect of internal and external treatment of traditional Chinese medicine combined with conventional Western medicine for chronic heart failure (CHF) in aged patients with qi-yin deficiency,blood stasis and damp obstruction. MethodsOne hundred and thirty-six aged CHF patients with qi-yin deficiency,blood stasis and damp obstruction were randomly divided into treatment group and control group with 68 cases in each group. The control group was treated with conventional Western medicine,and the treatment group was treated with Qiangxin Ⅱ Decoction,foot bath with herbs and point application with Erwu Wenyang Plaster on the basis of the treatment measures in the control group. The two groups were treated for 2 months. The clinical efficacy and adverse drug reactions were observed,and these indices were compared such as the cardiac function,walking distance of 6 min,levels of serum B natriuretic peptide (BNP),C-reactive protein (CRP) and cardiac troponin I (cTnI). Results:① There were 124 patients,62 patients in each group,who finally completed the trial. ②The total effective rate in the treatment group was significantly higher than that of the control group (91.93% vs 75.80%,P<0.05). ③After treatment,the left ventricular ejection fraction (LVEF) of the treatment group was significantly higher than that of the control group,while the left ventricular end-diastolic diameter (LVEDD) and left ventricular end-systolic diameter (LVESD) of the treatment group were significantly lower than those of the control group (P<0.05). ④After treatment,the walking distance of 6 min in the treatment group was significantly longer than that in the control group (P<0.05). ⑤The levels of serum BNP,CRP and cTnI in the treatment group were lower than those of the control group (P<0.05). ⑥ There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion:The internal and external treatment with traditional Chinese medicine combined with conventional Western medicine can significantly improve clinical efficacy and exercise tolerance,ameliorate cardiac function,reduce levels of serum BNP,CRP and cTnI,and has better safety for CHF in aged patients with qi-yin deficiency,blood stasis and damp obstruction.
强心Ⅱ号汤穴位敷贴足浴依那普利慢性心力衰竭临床疗效
Qiangxin II Decoctionpoint applicationherbal foot-bathEnalaprilchronic heart failureclinical efficacy
0
浏览量
169
下载量
0
CSCD
11
CNKI被引量
关联资源
相关文章
相关作者
相关机构