Objective:To analyze the application characteristics and rules of the meridians and acupoints of acupuncture and moxibustion in the treatment of chronic obstructive pulmonary disease by data mining technology. MethodsThe database of acupuncture-moxibustion prescriptions was established by collecting the modern literatures about the treatment of chronic obstructive pulmonary disease with acupuncture and moxibustion. The application characteristics and rules of the meridians and acupoints in the treatment of chronic obstructive pulmonary disease with acupuncture and moxibustion were analyzed by association rules in data mining technology.  Results:①A total of 104 prescriptions of acupuncture and moxibustion for treating chronic obstructive pulmonary disease were collected, including 51 acupoints and 552 total application frequency, and the acupoints of bladder meridian, conception vessel and stomach meridian were the most frequently used acupoints. ②The local selection of acpoints was dominant. Among them, the acupoints on the back and chest and abdomen accounted for 47.46% and 17.03% of the total acupoints, respectively. The higher application frequency was Feishu (BL13), Zusanli (ST36), Dingchuan (EX-B1) and Shenshu (BL23) acupoints in turn. ③The selection of specific acupoints showed absolute advantage, which accounted for 83.7% of the selected acupoints. The higher application frequency was back-shu point, crossing points and five-shu points in turn, and the supportive degree between five-shu points and crossing points was the highest.  Conclusion:It is reasonable and feasible to apply data mining technology in modern clinical literature research of acupuncture and moxibustion for treating chronic obstructive pulmonary disease, which can provide the basis for modern clinical research and treatment.