Infertility that caused by excess seven emotions induced internal injuries can be called as infertility due to depression syndrome. Emotional stagnation and stagnation of liver qi are most likely to affect menstruation,or lead to infertility,or even abortion. Adjusting emotion can also regulate the menstruation and pregnancy. The treatment methods include suppressing qi and nourishing blood to reduce the mood of joy and anger,adjusting meridians and regulating spleen to remove the mood of depression and jealousy,nourishing blood for tranquillization and keeping the peaceful mind,and nourishing yin and cooling blood to inhibit ministerial fire. In addition,psychological therapy and other non-drug treatments are also very important. Modern psychosomatic medicine such as psychogenic infertility,as well as part of ovulation dysfunction,luteal phase defect,luteinizing unruptured follicle syndrome and other infertility,which involved mental and psychological factors,probably belong to the category of infertility due to depression syndrome.