Emotional factors can lead to menstrual disorders. Liver is considered as the innate basis of women,dysfunction of Chong and Ren meridian caused by excess of seven emotions is the physiological and pathological basis. The basic pathogenesis of menstrual disorders due to depression syndrome includes stagnation of liver qi transforming into fire,deficiency of both heart and spleen,blood stasis and phlegm stagnation,deficiency of qi and blood,liver and kidney. In the treatment,it needs the therapy with syndrome differentiation that taking into account of the specificity of uterine bleeding and amenorrhea,and it can not ignore the importance of emotional therapy. Menstrual disorders due to depression syndrome are mainly found in the functional diseases caused by mental and psychological factors in modern medicine,such as dysfunctional uterine bleeding,stress amenorrhea,and other mental disorders such as depression and anxiety.