Objective:To establish the optimum method of extracting chlorogenic acid from Jinyinhua (Lonicerae Japonicae Flos) by ionic liquid. MethodsThe conditions of extraction of chlorogenic acid from Jinyinhua (Lonicerae Japonicae Flos) by ionic liquid microwave and ionic liquid bath heating were investigated and optimized,respectively,and the comparison was made.  Results:The optimum extraction method was as followed:the composition proportion in aqueous solution of ionic liquid was V  / V water as 4/11,the ratio of liquid to material was 30,the extraction process was performed by 400 W microwave for 2.5 minutes. The average yield of chlorogenic acid was 3.238% under this processing condition.  Conclusion:The method is fast,environmentally friendly and energy saving,with higher extraction rate.