SHI Miao-juan, GUO Xin-xin, SHANG Jia-wei, et al. Review of lncRNA acting as competitive endogenous RNA in hepatocellular carcinoma regulation and mechanism research of Chinese medicine[J]. Shanghai Journal of Traditional Chinese Medicine, 2017,51(11):91-96.
SHI Miao-juan, GUO Xin-xin, SHANG Jia-wei, et al. Review of lncRNA acting as competitive endogenous RNA in hepatocellular carcinoma regulation and mechanism research of Chinese medicine[J]. Shanghai Journal of Traditional Chinese Medicine, 2017,51(11):91-96.DOI:
Long noncoding RNA (lncRNA),as competitive endogenous RNA (ceRNA),can interact with miRNA(lncRNA/miRNA/mRNA)and play the role in the regulation of hepatocellular carcinoma. This paper reviews the functions and mechanisms of lncRNA/miRNA/mRNA in the occurrence and development of hepatocellular carcinoma,and researches about lncRNA/miRNA/mRNA regulation pathway and Chinese medicine mechanism. lncRNA/miRNA/mRNA enrich the occurrence and development mechanism of hepatocellular carcinoma,and provide novel insight into the diagnosis and therapy of hepatocellular carcinoma.
关键词
lncRNAceRNAmiRNA肝癌中药机制综述
Keywords
lncRNAceRNAmiRNAhepatocellular carcinomaChinese medicine mechanismreview