Objective:To observe the clinical efficacy of Sanhuang Capsule combined with Jinhuang Ointment in the treatment of acute gouty arthritis with syndrome of dampness-heat blockage. Methods 60 patients of acute gouty arthritis with syndrome of dampness-heat blockage were randomly divided into the treatment group and control group,30 cases in each group. The control group was orally treated with diclofenac sodium,and the treatment group was additionally treated with Sanhuang Capsule for oral administration and Jinhuang Ointment for external application based on the treatment for the control group,with a course of 10 days. The clinical efficacy was observed ,and the changes of TCM syndrome score,visual analogue scale(VAS)scores(pain and activity limitation),score of joint swelling and the levels of the related biochemical indexes including blood uric acid (BUA),erythrocyte sedimentation rate (ESR) and C reactive protein (CRP) were compared.  Results: ①The clinical tota1 effective rate was 93.33％ in the treatment group and 70.00％ in the control group. The clinical efficacy of the treatment group was significantly better than that of the control group(P<0.05). ②After treatment,there was statistically significant difference on TCM syndrome score between the two groups,and the score of the treatment group was obviously lower than that of the control group(P<0.05). ③After treatment,there were statistically significant differences on the VAS scores of pain and activity limitation and the score of joint swelling between the two groups,and the scores of the treatment group were significantly lower than those of the control group(P<0.05). ④After treatment,there were statistically significant differences on the levels of BUA,ESR and CRP between the two groups,and the levels of the treatment group were significantly lower than those of the control group(P<0.05).  Conclusion:Sanhuang Capsule with oral administration and Jinhuang Ointment with external application combined with western medicine can be used in the treatment of acute gouty arthritis with syndrome of dampness-heat blockage,which can significantly relieve the clinical symptoms and decrease the level of uric acid.