Objective:To study the antitussive,expectorant and antiasthmatic effects of Xijie Huatan Pingchuan Cataplasm. Methods50 Kunming mice(25 male and 25 female)were randomly divided into the blank control group,Xijie Huatan Pingchuan Cataplasm groups with high-,medium- and low-dose and Amidi group as positive control. One day before the experiment,the back hair of all the mice were shaved,and then corresponding drugs were applied externally on lung-shu point of mice in the treatment groups and positive control group. The antitussive and expectorant effects of Xijie Huatan Pingchuan Cataplasm were investigated by the methods of mice cough caused by concentrated ammonia water and mice tracheal phenol red excretion. 40 rats(20 male and 20 female)were treated with the same grouping and administration described previously. Rat model of asthma was replicated by the methods of ovalbumin(OVA) sensitization and excitation. The latent period of asthma induced by aerosol inhalation in rats was calculated. The contractile response of rat tracheal spiral strips to acetylcholine was observed.  Results:For the antitussive test, compared with the blank control group,the cough times of mice were significantly inhibited in the Xijie Huatan Pingchuan Cataplasm groups with different doses and positive control group(P<0.05,P<0.01),the response latency of mice was significantly prolonged. There were statistically significant differences on the cough times and latent period between the Xijie Huatan Pingchuan Cataplasm group with low dose and Xijie Huatan Pingchuan Cataplasm groups with medium- and high-dose(P<0.05),which suggested that the effects presented in a dose-dependent manner. For the expectorant test,compared with the blank control group,the excretion of phenol red in mice airway in the Xijie Huatan Pingchuan Cataplasm groups with medium- and high-dose and positive control group was obviously increased(P<0.05,P<0.01),which suggested that Xijie Huatan Pingchuan Cataplasm showed expectorant effect. There were statistically significant differences on the excretion of phenol red between the Xijie Huatan Pingchuan Cataplasm group with low dose and Xijie Huatan Pingchuan Cataplasm groups with medium- and high-dose(P<0.05). For the asthma experiment,compared with the blank control group,the incubation period of asthma was obviously prolonged in the Xijie Huatan Pingchuan Cataplasm groups with different doses and positive control group(P<0.05),and the rats number of falling and shock was small. There was statistically significant difference on the incubation period of asthma between the Xijie Huatan Pingchuan Cataplasm group with low dose and high dose(P<0.05). Compared with the blank control group,the contraction of rat tracheal smooth muscle was all obviously suppressed in the Xijie Huatan Pingchuan Cataplasm groups with different doses and positive control group(P<0.05),which suggested that Xijie Huatan Pingchuan Cataplasm could suppress the contraction of airway smooth muscle,relax the airway smooth muscle and reduce airway responsiveness. There were statistically significant differences on the suppression of contraction of rat tracheal smooth muscle between the Xijie Huatan Pingchuan Cataplasm group with low dose and Xijie Huatan Pingchuan Cataplasm groups with medium- and high-dose(P<0.05).  Conclusion: Xijie Huatan Pingchuan Cataplasm shows pharmacodynamic actions of antitussive, expectorant and antiasthmatic effects.