This article applied the therapeutic principle of Shaoyin diseases to the differentiation and treatment of nephrotic syndrome. Sini Decoction and associated prescriptions were mainly used in the method of restoring and reversing yang for the treatment of deficiency of yin and yang.Zhenwu Decoction and associated prescriptions were mainly used in the method of warming yang and dispeling dampness for the treatment of yin excess and yang deficiency syndrome with dampness.Prescriptions as Huanglian Ejiao Decoction,Zhuling Decoction,Zhufu Decoction and Kujiu Decoction were used in the method of nourishing yin and clearing fire for the treatment of heat-conversion syndrome of Shaoyin.