Objective:To observe the clinical efficacy of Yiqi Tongluo Recipe combined with routine western medicines on coronary slow flow phenomenon. MethodsFifty-nine patients with coronary slow flow phenomenon were randomly divided into the treatment group (30 cases) and control group(29 cases). The control group was treated with routine western medicines,while the treatment group was treated with Yiqi Tongluo Recipe additionally based on the treatment for the control group. The therapeutic course of both groups was three months. The clinical efficacy and electrocardiogram were observed,and the changes of high sensitive C reactive protein (hs-CRP),flow-mediated dilation(FMD),positive rate of treadmill exercise test (TET),correct TIMI frame count(CTFC)were compared.  Results:①The total effective rate of the treatment group and the control group were 93.33% and 75.86% respectively. There was statistically significant difference on the clinical efficacy between the two groups,and the effect of the treatment group was better than that of the control group(P<0.05). ②The total effective rate of electrocardiogram in the treatment group and the control group were 90.00% and 72.41% respectively. There was statistically significant difference on the electrocardiogram efficacy between the two groups,and the effect of the treatment group was better than that of the control group(P<0.05). ③After treatment,there were statistically significant differences on the level of hs-CRP,FMD,CTFC and TET between the two groups,and the effects of the treatment group were significantly better than those of the control group(P<0.05).  Conclusion:Yiqi Tongluo Recipe combined with routine western medicines shows good effects in the treatment of coronary slow flow phenomenon.