Objective:To observe the effects of Baiyu Shenjing Maitong Decoction combined with conventional western medicine on serum adiponectin in patients with coronary heart disease of phlegm and blood stasis syndrome. MethodsSixty patients with coronary heart disease of phlegm and blood stasis syndrome were randomly divided into the treatment group and control group,30 cases in each group. The control group was treated with conventional western medicine,and the treatment group was treated with Baiyu Shenjing Maitong Decoction combined with conventional western medicine,with a course of 2 months. The clinical efficacy was observed and the changes of TCM syndrome scores,blood lipid indexes and adiponectin level were compared.  Results:①The total effective rate in the treatment group and control group was 90.0% and 70.0% respectively；there was statistically significant difference on the clinical efficacy between the two groups (P<0.05). ②Comparison of treatment before and after,there were statistically significant differences on the palpitations, shortness of breath, chest epigastric fullness, body weakness and total score in the treatment group(P<0.05),there were statistically significant differences on the chest pain, shortness of breath, chest epigastric fullness and total score in the control group(P<0.05). Comparison between the two groups,there were statistically significant differences on the chest epigastric fullness, body weakness and total score after treatment (P<0.05). ③Comparison of treatment before and after,the differences on the blood lipid indexes in both groups were not statistically significant(P>0.05),but there was statistically significant difference on the adiponectin in both groups(P<0.05). Comparison between the two groups,there was statistically significant difference on the adiponectin after treatment (P<0.05).  Conclusion:Baiyu Shenjing Maitong Decoction combined with conventional western medicine can effectively alleviate the clinical symptoms of coronary heart disease patients with phlegm and blood stasis syndrome,and shows a certain effect of up-regulation of serum adiponectin.