九宝丸加减方治疗风痰蕴肺型小儿感染后咳嗽的临床研究

杨周剑; 姚静雯; 石李; 顾静雯

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九宝丸加减方治疗风痰蕴肺型小儿感染后咳嗽的临床研究

信息窗 | 更新时间：2022-08-31

- 九宝丸加减方治疗风痰蕴肺型小儿感染后咳嗽的临床研究
- Clinical study of modified Jiubaowan pill in the treatment of post-infection cough in child with anemogenous phlegm accumulation in lung
- 上海中医药杂志 2016年50卷第8期页码：60-63
- 作者机构：
  
  1. 上海市浦东新区中医医院儿科,上海,201200
  2. 上海市浦东新区中医医院药剂科,上海,201200
  3. 上海中医药大学附属龙华医院儿科,上海,201203
  4. 上海市第七人民医院儿科,上海,200137
- 作者简介：
- 基金信息：
  
  上海市卫生局杏林新星计划项目(ZY3-RCPY-2-2064);上海市浦东新区名中医继承人培养项目(PDZYXK-6-2014018);上海市浦东新区国家中医药发展综合改革实验区内涵建设项目(ZY3-CCCX2-1001-2)
- DOI：
  中图分类号：
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杨周剑, 姚静雯, 石李, 等. 九宝丸加减方治疗风痰蕴肺型小儿感染后咳嗽的临床研究[J]. 上海中医药杂志, 2016,50(8):60-63.

YANG Zhou-jian, YAO Jing-wen, SHI Li, et al. Clinical study of modified Jiubaowan pill in the treatment of post-infection cough in child with anemogenous phlegm accumulation in lung[J]. Shanghai Journal of Traditional Chinese Medicine, 2016,50(8):60-63.
杨周剑, 姚静雯, 石李, 等. 九宝丸加减方治疗风痰蕴肺型小儿感染后咳嗽的临床研究[J]. 上海中医药杂志, 2016,50(8):60-63. DOI：

YANG Zhou-jian, YAO Jing-wen, SHI Li, et al. Clinical study of modified Jiubaowan pill in the treatment of post-infection cough in child with anemogenous phlegm accumulation in lung[J]. Shanghai Journal of Traditional Chinese Medicine, 2016,50(8):60-63. DOI：

摘要

目的：观察九宝丸加减方治疗风痰蕴肺型小儿感染后咳嗽的临床疗效。方法：将200例风痰蕴肺型感染后咳嗽患儿按照咳嗽轻重程度,分别随机分入轻度咳嗽治疗组、轻度咳嗽对照组及重度咳嗽治疗组、重度咳嗽对照组。治疗组均予九宝丸加减方,对照组均予白三烯受体拮抗剂。两组疗程均为14天。观察临床疗效,比较中医证候积分的变化情况。结果：①最终完成试验者,轻度咳嗽治疗组47例、对照组46例,重度咳嗽治疗组44例、对照组44例。②轻度咳嗽治疗组、对照组临床总有效率分别为85.11%和86.96%；组间临床疗效比较,差异无统计学意义(P>0.05)。重度咳嗽治疗组、对照组临床总有效率分别为75.00%和56.82%；组间临床疗效比较,差异有统计学意义(P<0.05)。③轻度咳嗽患儿治疗前后组内比较,两组中医证候积分水平差异均有统计学意义(P<0.05)；组间治疗后比较,中医证候积分水平差异无统计学意义(P>0.05)。重度咳嗽患儿治疗前后组内比较,两组中医证候积分水平差异均有统计学意义(P<0.05)；组间治疗后比较,中医证候积分水平差异有统计学意义(P<0.05)。结论：九宝丸加减方治疗小儿感染后咳嗽的疗效满意,可减轻咳嗽症状,且对重度咳嗽疗效更显著。

Abstract

Objective:To observe the efficacy of modified Jiubaowan in the treatment of post-infection cough in child with anemogenous phlegm accumulated in lung. MethodsAccording to the degree of cough severity, 200 subjects were randomized into the treatment group with mild symptom, control group with mild symptom, treatment group with severe symptom, control group with severe symptom. Modified Jiubaowan was applied in the two treatment groups,while leukotriene receptor antagonist in the two control groups,with a course of 14 days. The clinical efficacy was observed and the scores of TCM syndrome were compared. Results:①Among the patients who complete the whole test,there were 47 patients in the treatment group with mild symptom and 46 patients in the control group with mild symptom;44 patients in the treatment group with severe symptom and 44 patients in the control group with severe symptom.②The total effective rate of treatment group with mild symptom was 85.11%,and control group with mild symptom was 86.96%. There was no statistically significant difference in clinical efficacy between these two groups (P>0.05). The total effective rate of treatment group with severe symptom was 75%,and control group with severe symptom was 56.82%. There was statistically significant difference in clinical efficacy between these two groups (P<0.05). ③In the two groups of mild symptom,compared with before treatment within groups,there was statistically significant difference in the score of TCM syndrome in both group after treatment (P<0.05); compared between groups after treatment,there was no statistically significant difference in the score of TCM syndrome(P>0.05). In the two groups of severe symptom,compared with before treatment within groups,there was statistically significant difference in the score of TCM syndrome in both group after treatment (P<0.05); compared between groups after treatment,there was statistically significant difference in the score of TCM syndrome(P<0.05). Conclusion:Modified Jiubaowan showed good efficacy in the treatment of post-infection cough in child,which relieved cough symptoms, and it was more effective on severe cogh children.

关键词

小儿感染后咳嗽风痰蕴肺九宝丸少阳病

Keywords

childpost-infection coughanemogenous phlegm accumulated in lungJiubaowanshaoyang disease

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