1. 浙江中医药大学附属宁波市中医院重症监护科,浙江,宁波,315010
2. 浙江中医药大学附属第一医院呼吸科,浙江,杭州,310006
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吴燕, 王真, 吴力, 等. 小承气汤加减对重型颅脑损伤术后肺部感染影响的临床观察[J]. 上海中医药杂志, 2016,50(7):44-46.
WU Yan, WANG Zhen, WU Li, et al. Clinical observation of Xiao Cheng-Qi Decoction on the effect of pulmonary infections in patients with postoperative severe craniocerebral injury[J]. Shanghai Journal of Traditional Chinese Medicine, 2016,50(7):44-46.
吴燕, 王真, 吴力, 等. 小承气汤加减对重型颅脑损伤术后肺部感染影响的临床观察[J]. 上海中医药杂志, 2016,50(7):44-46. DOI:
WU Yan, WANG Zhen, WU Li, et al. Clinical observation of Xiao Cheng-Qi Decoction on the effect of pulmonary infections in patients with postoperative severe craniocerebral injury[J]. Shanghai Journal of Traditional Chinese Medicine, 2016,50(7):44-46. DOI:
目的:观察小承气汤加减联合西医常规治疗重型颅脑损伤术后肺部感染的临床疗效。 方法:将67例重型颅脑损伤术后肺部感染患者随机分为治疗组(34例)和对照组(33例)。两组均给予西医常规治疗,治疗组加服小承气汤加减。两组疗程均为7天,观察临床疗效,比较相关生化指标,包括白细胞计数(WBC)、超敏C反应蛋白(CRP)、降钙素原(PCT)以及临床肺部感染评分(CPIS评分)的变化情况。 结果:①治疗组、对照组临床总有效率分别为93.33%和70.00%;组间临床疗效比较,差异有统计学意义,治疗组优于对照组(P<0.05)。②组间治疗3天后比较,PCT水平差异有统计学意义(P<0.05);组间治疗7天后比较,WBC、CRP、PCT及CPIS评分水平差异有统计学意义(P<0.05)。 结论:小承气汤加减联合西医常规治疗重型颅脑损伤术后肺部感染,疗效满意,可显著减轻肺部感染及炎症反应。
Objective:To observe the clinical efficacy of Xiao Cheng-Qi decoction combined conventional western medecine in the treatment of pulmonary infections on patients with postoperative severe craniocerebral injury. Methods 67 cases of pulmonary infections on patients with postoperative severe craniocerebral injury were randomly divided into treatment group(34 cases) and control group(33 cases). Conventional western medecine treatment was given to both groups,and additionally,Xiao Cheng-Qi decoction was applied to treatment group, with a course of one week. The clinical efficacy was observed and changes of the levels of correlated biochemical indexes including WBC、CRP、PCT and clinical pulmonary infection score(CPIS)between two groups were compared. Results: ①The effective rate of the treatment group is 93.3%,and the control group is 70.0%,the difference between two groups was statistically significant (P<0.05). ②After three-day treatment,the levels of PCT obviously decreased in the treatment group than the control group(P<0.05). After seven-day treatment,the levels of WBC、CRP、PCT and CPIS significantly decreased in the treatment group than the control group(P<0.05). Conclusion:Xiao Cheng-Qi decoction combined conventional western medecine could be used to treat pulmonary infections on patients with postoperative severe craniocerebral injury, which significantly relieve pulmonary infections and inflammatory response in patients.
重型颅脑损伤术后肺部感染小承气汤痰热壅肺通腑法经方试验
postoperative severe craniocerebral injurypulmonary infectionsXiao Cheng-Qi decoctionphlegm- heat obstructing lungspurgative methodtest of classical prescription
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