Objective:To observe the clinical effects of “Xingqii Lishui Powder” on topical treatment of malignant ascites. MethodsSixty subjects were randomly divided into treatment group and control group, 30 cases in each group. The control group was treated with spironolactone and furosemide tablet, and the treatment group was treated by “Xingqi Lishui Powder” on navel compression besides the treatment in the control group, with a course 10 days. The TCM symptom score and abdominal pain score were observed before and after treatment.  Results:①The effective rates of treatment group and control group were 73.33% and 13.33% respectively, with better effects in the treatment group than in the control group(P<0.05). ②There were striking differences in TCM syndrome score and abdominal pain score between before and after treatment in both groups(P<0.05); after treatment, there was a significant difference between treatment group and control group(P<0.05).  Conclusion:“Xingqi Lishui Powder” on navel compression in effective to treat cancerous ascites in relieving ascites and improving the quality of life.