Objective:To observe the clinical effects of “Yangyin Huatan Xifeng Decoction” in the treatment of recurrent hepatic encephalopathy. MethodsEight-six subjects were randomly divided into treatment group and control group, 43 cases in each group. Control group was treated with rifaximin and lactulose, while treatment group was given “Yangyin Huatan Xifeng Decoction”, with a course of 6 months. The occurrence of hepatic encephalopathy was observed and the number-connection test and the plasma level of ammonia were compared during the treatment.  Results:①Seventy-four cases completed the whole trials, among which 37 cases were in treatment group and 37 cases were in control group. ②During the course of treatment, the average attack times of hepatic encephalopathy in the treatment group were significantly fewer than that of the control group(P<0.05). ③The differences of NCT-A test time, DST test scores and blood ammonia levels within each group before and after treatment were statistically significant(P<0.05). But there were no significant differences in the NCT-A test time and DST test scores between two groups. Compared with the control group after treatment, the blood ammonia levels in the treatment group were significantly decreased(P<0.05).  Conclusion:“Yangyin Huatan Xifeng Decoction” works well on recurrent encephalopathy in reducing the attack frequency and blood ammonia.