This paper aims at summarizing Prescription drug characteristics of Unpublished Ye’s Medical Records written by Ye Tian-shi on treating female disease such as using a variety of drugs, plain but very clever, using the classic prescription, flexible change, pay attention to the foundation of innateness and postnatal, regulating the eight extra-meridians, harmonic qi and blood, be good at applying the Chinses angelica and Fuling, and so on. Summarizing these characteristics will contribute to understand and study Ye’s thoughts about gynecology and to guide clinical practice.