Objective:To observe the clinical effects on cervical HPV infection with Jiawei Jianpi Decoction combined with XinFuNing. Methods60 cases of patients with cervical HPV infection were randomly divided into treating group(treated with Jiawei Jianpi Decoction plus XinFuNing) and control group(treated with XinFuNing only), 30 cases in each group. The treatment period of each group is 3 months, in which observing the clinical efficacy, HPV turning rate and the review of TCM syndrome.  Results:①The total effective rate of the treating group(86.67%) is higher than the control group(43.33%)(P<0.05). ②The turning rate of cervical HPV of the treating group(80%) is higher than the control group(40%)(P<0.05). ③The score of the treating group is significantly reduced on the capacity of leucorrhea , the peculiar smell of leucorrhea , the yellow color of leucorrhea and the total score(P<0.05),and at the same time there is no obvious difference in each score of the control group. Compared between groups after treatment, the scores on the capacity of leucorrhea , the peculiar smell of leucorrhea , the yellow color of leucorrhea and the total score of the treating group were lower than the control group(P<0.05).  Conclusion:The effects of Jiawei Jianpi Decoction combined with XinFuNing used in treating cervical HPV infection is significantly more effective on enhancing the turning rate of HPV and improving TCM syndrome than the effects of using XinFuNing only.