Objective:To observe the clinical curative effect of “Danshao Shugan Granule” for the treatment of nonalcoholic fatty liver disease. MethodsWe selected 80 cases of nonalcoholic fatty liver patients which were randomly divided into treatment group(40 cases)and control group. The treatment group was treated with “Danshao Shugan granule” and the control group was treated with Atorvastatin Tablets.The period of treatment was 3 months.The clinical efficacy, syndrome score, the changes of blood lipid and liver function were observed in the two groups.  Results:①The total effective rate of the treatment and control groups were 90.0% and 85.0% respectively, and there was no significant difference in efficacy between the two groups (P>0.05). ②After treatment,the symptom score was obvious reduced in the treatment and control group compared with those before treatment(P<0.05) . ③After the treatment, the levels of serum total cholesterol and triglyceride were obviously decreased than before(P<0.05)and the level of control group was lower than that of treatment group; ALT, AST and GGT was decreased in the treatment group compared with those before treatment(P<0.05) and lower than that of control group.  Conclusion:“Danshao Shugan Granule” has certain therapeutic effect for nonalcoholic fatty liver disease, and could improve lipid metabolism and protect liver function.