Objective:To observe the clinical effects of “Jianpi Huoxue Decoction” on treating lipid metabolism disorder after menopause. Methods50 patients were randomly divided into observation group and control group, 25 in each group. The control group was treated with Simvastatin Tablets and the observation group was treated with “Jianpi Huoxue Decoction”, with 3 months of treatment peoriod. The changes of blood lipid, sex hormone and body weighty were observed.  Results:Intra-group comparison before and after the treatment, there was significance in TC, TG and LDL-C(P,<,0.05)but there was no significance in HDL-C(P,>,0.05)；comparsision between groups after treatment, there was significance in TC and LDL-C(P,<,0.05). Intra-group comparison before treatment, there was significance in E,2, level and body weighty in observation group(P,<,0.05), but there was no significance in each index in control group(P,>,0.05); comparsision between groups after treatment, there was significance in E,2, level and body weighty(P,<,0.05).  Conclusion:the effect of “Jianpi Huoxue Decoction” on treating lipid metabolism disorder after menopause was satisfactory.