Objective:To observe the clinical efficacy of “Jianfu Yin” with Viagr in the treatment of LOH intractable ED. Methods60 cases were randomized into treatment group and control group, 30 in each group. The control group was treated with “Zuogui Pill” combined with Viagr, and the treatment group was treated with “Jianfu Yin” combined with Viagr,both groups with the course of 2 months.The rigidity of penis levels, scores of IIEF-5 scores and SILOH were observed.  Results:① After the treatment of 2 months, there were 22 cases reached III level in treatment group and 17 cases in control group; there was significant difference in the comparison of rigidity of penis between the two groups(P<0.05), and the treatment group was better than the control group. ② Compared before and after the treatment in each group, the scores of IIEF and SILOH both obviously increased(P<0.05); while compared before and after the treatment between the two groups, score of IIEF in treatment group higher than that of control group, and the difference was significant(P<0.05).  Conclusion:The clinical efficacy of “Jianfu Yin” with Viagr in the treatment of LOH intractable ED was satisfactory.