Objective:To observe the clinical efficacy of “Compound Danshen Dripping Pills” and Amlodipine Tablets in the treatment of primary hypertension with positive electrocardiogram treadmill exercise tests. MethodsOne hundred and forty-six subjects were randomized into two groups:control group in which in which 66 cases were treated with Amlodipine Tablets, and treatment group in which 80 cases were treated with Amlodipine Tablets and “Compound Danshen Dripping Pills”, with a course of four weeks. The electrocardiogram efficacy, peak systolic pressure and the indexes of electrocardiogram treadmill exercise tests were observed.  Results:① The total effective rate for electrocardiogram was 96.25% in the treatment group and 83.33% in the control group, with better efficacy in the treatment group than in the control group(P<0.05). ②After treatment, the peak systolic pressures were reduced in both groups(P<0.05), with lower pressure in the treatment group than in the control group(P<0.05). ③After treatment, the indexes of electrocardiogram treadmill exercise tests were improved in both groups(P<0.05), with more significant improvement in the treatment group than in the control group(P<0.05).  Conclusion:Combined “Compound Danshen Dripping Pills” and Amlodipine Tablets is effective for hypertension and heart protection.