Objective:To observe the therapeutic effect of manipulation on temporomandibular disorders,and the range of temporomandibular joints’ motion on imageology  Methods:60 patients are randomly divided into a manipulation group (Group A) and a semiconductor laser group (Group B) with 30 cases in each one then observe through therapeutic effects, Fricton’s Craniomandibular Index and the range of temporomandibular joints’motion  Results:The total effective rate is 93.3% in Group A and 70.0% Group B. The therapeutic effect of Group A is better than Group B (P<0.05). Both Groups’ Fricton’s Craniomandibular Index numbers are lower after treatment (P<0.05), and Group A is lower than Group B (P<0.05). Both Groups’ range distance increase after treatment (P<0.05), and Group A is longer than Group B (P<0.05)  Conclusion:Manipulation can improve the clinical symptoms of temporomandibular disorder and the function of temporomandibular joints.