1. 黑龙江中医药大学附属第一医院重点学科专科办公室,黑龙江,哈尔滨,150040
2. 黑龙江中医药大学中医药研究院药理室,黑龙江,哈尔滨,150040
3. 黑龙江省中医医院呼吸科,黑龙江,哈尔滨,150036
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田伟, 张淑香, 江柏华. 清肺止咳灵糖浆对慢性支气管炎急性发作期止咳祛痰平喘作用的实验研究[J]. 上海中医药杂志, 2015,49(6):81-84.
TIAN Wei, ZHANG Shu-xiang, JIANG Bai-hua. Antitussive, apophlegmatic and antiasthmatic effects of “Qingfei Zhikeling Syrup” on acute attack of chronic bronchitis[J]. Shanghai Journal of Traditional Chinese Medicine, 2015,49(6):81-84.
田伟, 张淑香, 江柏华. 清肺止咳灵糖浆对慢性支气管炎急性发作期止咳祛痰平喘作用的实验研究[J]. 上海中医药杂志, 2015,49(6):81-84. DOI:
TIAN Wei, ZHANG Shu-xiang, JIANG Bai-hua. Antitussive, apophlegmatic and antiasthmatic effects of “Qingfei Zhikeling Syrup” on acute attack of chronic bronchitis[J]. Shanghai Journal of Traditional Chinese Medicine, 2015,49(6):81-84. DOI:
目的:研究清肺止咳灵糖浆对慢性支气管炎急性发作期的止咳祛痰平喘作用 方法:通过对SO,2,致小鼠咳嗽、毛细玻管法测大鼠排痰量、豚鼠磷酸组胺喷雾引喘潜伏期的观察,研究清肺止咳灵糖浆对慢性支气管炎急性发作期的止咳祛痰平喘作用 结果:清肺止咳灵糖浆能明显延长小鼠对SO,2,刺激引起咳嗽的潜伏期(P,<,0.05),能显著增加大鼠气管排痰量(P,<,0.05),能明显延长豚鼠磷酸组胺喷雾引喘潜伏期(P,<,0.05) 结论:清肺止咳灵糖浆对慢性支气管炎急性发作期具有明显的止咳祛痰平喘作用。
Objective:This paper is to research antitussive, apophlegmatic and antiasthmatic effects of “Qingfei Zhikeling Syrup” on chronic bronchitis acute attack Methods:Thre Methods: were used in this experiment include the observation of cough that was induced by SO,2, in mice, observation on the phlegm expelling in rats by using glass capillary and the observation of incubation period of guinea pig induced by histamine phosphate Results:“Qingfeizhikeling Syrup” can significantly prolong the mice to SO,2, stimulation caused cough incubation period (P,<,0.05), can significantly increase the rat trachea sputum volume(P,<,0.05), can obviously prolong the guinea pig histamine phosphate spray out of the incubation period(P,<,0.05) Conclusion:“Qingfeizhikeling Syrup” of chronic bronchitis acute phase has obvious Antitussive, apophlegmatic and anti-asthmatic effect.
清肺止咳灵慢性支气管炎急性发作期止咳祛痰平喘
“Qingfeizhikeling Syrup”chronic bronchitisacute attackantitussiveexpectorantantiasthmatic
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