Clinical observation of “Qutan Dingxian Decoction” in treating intractable epilepsy

CHEN Min; HUANG Ning-jing; ZHANG Xiao-jing

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Clinical observation of “Qutan Dingxian Decoction” in treating intractable epilepsy

更新时间：2022-08-31

- Clinical observation of “Qutan Dingxian Decoction” in treating intractable epilepsy
- Shanghai Journal of Traditional Chinese Medicine Vol. 50, Issue 8, Pages: 43-45(2016)
- 作者机构：
  
  1. 上海中医药大学附属市中医医院脑病科,上海,200071
  2. 上海中医药大学附属普陀医院神经内科,上海,200062
- 作者简介：
- 基金信息：
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CHEN Min, HUANG Ning-jing, ZHANG Xiao-jing. Clinical observation of “Qutan Dingxian Decoction” in treating intractable epilepsy. [J]. Shanghai Journal of Traditional Chinese Medicine 50(8):43-45(2016)
DOI：

CHEN Min, HUANG Ning-jing, ZHANG Xiao-jing. Clinical observation of “Qutan Dingxian Decoction” in treating intractable epilepsy. [J]. Shanghai Journal of Traditional Chinese Medicine 50(8):43-45(2016) DOI：

摘要

目的：观察祛痰定痫汤治疗难治性癫痫的临床疗效。方法：将61例难治性癫痫患者随机分为治疗组(30例)和对照组(31例)；两组均给予常规抗癫痫治疗,治疗组同时口服祛痰定痫汤,疗程12周。观察两组治疗前后癫痫发作频率和脑电图异常疗效。结果：①治疗组癫痫发作频率疗效的总有效率为73.33%,对照组为41.93%；治疗组癫痫发作频率疗效优于对照组(P<0.01)。②治疗后,两组脑电图异常情况明显改善(P<0.05,P<0.01),且治疗组脑电图的改善较对照组显著(P<0.05)。结论：祛痰定痫汤治疗难治性癫痫能减少发作频率,改善脑电图。

Abstract

Objective:To observe the clinical efficacy of “Qutan Dingxian Decoction” in the treatment of intractable epilepsy. MethodsSixty-one subjects were randomized into the treatment group(30 cases) and control group(31 cases), which all treated with routine modalities; besides, the treatment group was also given “Qutan Dingxian Decoction”, with a course of 12 weeks. The efficacy on frequency of epileptic seizures and abnormal electroencephalogram was observed before and after treatment. Results:①For the frequency of epileptic seizures, the effective rate was 73.33% in the treatment group and 41.93% in the control group, the efficacy in the treatment group was than better the control group(P<0.01). ②After treatment, the abnormal electroencephalogram was obviously improved in both groups(P<0.05, P<0.01), with more significant improvement in the treatment group than in the control group(P<0.05). Conclusion:“Qutan Dingxian Decoction” could be used in the treatment of intractable epilepsy which reduced epileptic seizure and improved electroencephalography.

关键词

祛痰定痫汤难治性癫痫脑电图

Keywords

“Qutan Dingxian Decoction”intractable epilepsyelectroencephalogram

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School of Acupuncture-moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine

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