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1.辽宁中医药大学(辽宁 沈阳 110847)
2.辽宁中医药大学附属第二医院(辽宁 沈阳 110034)
韩驰,男,硕士研究生,主要从事中医药治疗风湿免疫性疾病临床工作
赵用,主任医师,硕士研究生导师;E-mail:28915134@qq.com
收稿:2025-09-28,
网络首发:2026-08-03,
纸质出版:2026-08-10
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韩驰,刘书源,孙贵炎,等.基于“白气微泄”理论探讨轻型系统性红斑狼疮的病机与辨治[J].上海中医药杂志,2026,60(8):58-64.
Han Chi,Liu Shuyuan,Sun Guiyan,et al.Exploration on pathogenesis, diagnosis and treatment of mild systemic lupus erythematosus based on theory of "mild leakage of white qi"[J].Shanghai Journal of Traditional Chinese Medicine,2026,60(8):58-64.
韩驰,刘书源,孙贵炎,等.基于“白气微泄”理论探讨轻型系统性红斑狼疮的病机与辨治[J].上海中医药杂志,2026,60(8):58-64. DOI: 10.16305/j.1007-1334.2026.z20250928002.
Han Chi,Liu Shuyuan,Sun Guiyan,et al.Exploration on pathogenesis, diagnosis and treatment of mild systemic lupus erythematosus based on theory of "mild leakage of white qi"[J].Shanghai Journal of Traditional Chinese Medicine,2026,60(8):58-64. DOI: 10.16305/j.1007-1334.2026.z20250928002.
基于“白气微泄”理论辨治轻型系统性红斑狼疮(SLE)。梳理该理论的古籍内涵,“白气”即肺气,“微泄”指肺气轻微耗泄致卫气宣发失职、腠理不密,与轻型SLE“病位在表、邪浅证轻、脏腑未损”的病理特征高度契合;其核心病因病机在于“白气生成不足、白气耗泄加剧、卫郁气泄”;据此确立“微病微调”为核心治则,围绕“复白气循行、补白气耗损、防白气耗伤”构建诊疗框架,配套形成“玉屏风散合桑菊饮化裁方+宣肺护表洗方”的方药体系。并附验案1则。
This study adopts the theory of "mild leakage of white qi" for syndrome differentiation and therapeutic management of mild systemic lupus erythematosus (SLE). The ancient classical connotation of the aforementioned theory is elucidated: the term "white qi" corresponds to lung qi, while "mild leakage" refers to mild consumption and dissipation of lung qi that impairs the dispersion function of defensive qi and loosens cutaneous interstitial striae. This pathological essence is highly consistent with the pathological hallmark of mild SLE, namely superficial lesion localization, superficial pathogenic invasion with mild clinical presentations, and absence of substantial visceral injury. Its core etiology and pathogenesis fall into three categories: deficient biosynthesis of lung qi, aggravated consumption and leakage of lung qi, and defensive qi stagnation complicated with pathological qi dissipation. On this basis, the core therapeutic principle of minimal regulation for mild disorders is formulated, and a standardized diagnostic and therapeutic framework is established centering on three therapeutic objectives: restoring the physiological circulation of lung qi, replenishing consumed lung qi, and preventing progressive lung qi damage. A complete medication regimen is subsequently developed, comprising an oral modified formula derived from Yupingfeng Powder and Sangju Decoction as well as an external topical lotion for diffusing lung qi and consolidating the superficial defensive barrier. One proven case is presented.
Athanassiou P , Athanassiou L , Kostoglou-Athanassiou I , et al . Targeted cellular treatment of systemic lupus erythematosus [J]. Cells , 2025 , 14 ( 3 ): 210 .
中华医学会风湿病学分会 , 国家皮肤与免疫疾病临床医学研究中心 , 中国系统性红斑狼疮研究协作组 . 2020中国系统性红斑狼疮诊疗指南 [J]. 中华内科杂志 , 2020 , 59 ( 3 ): 172 - 185 .
国家皮肤与免疫疾病临床医学研究中心 , 中国系统性红斑狼疮研究协作组 , 中华医学会风湿病学分会 . 中国系统性红斑狼疮诊疗指南(2025版) [J]. 中华医学杂志 , 2025 , 105 ( 23 ): 1879 - 1906 .
张星 , 马月香 . 基于“肺主皮毛”探析汗与肺的相关性 [J]. 山东中医药大学学报 , 2021 , 45 ( 3 ): 331 - 335 .
张洪雨 , 罗婉婷 , 李一平 , 等 . 许铣以“白气微泄”理论辨治扁平疣经验 [J]. 中医杂志 , 2024 , 65 ( 22 ): 2294 - 2298 .
康鹏飞 , 秦明臻 , 孟佳 , 等 . 《黄帝内经》治未病之“微病”探讨 [J]. 中国医药导报 , 2021 , 18 ( 18 ): 155 - 159 .
李满意 , 刘红艳 , 陈传榜 , 等 . 蝶疮流注的证治 [J]. 风湿病与关节炎 , 2024 , 13 ( 3 ): 49 - 54 .
崔正九 , 吴德美 , 罗斐 , 等 . 基于“营卫生会”探讨儿童腺样体肥大病机与辨治 [J]. 陕西中医 , 2025 , 46 ( 9 ): 1243 - 1246 .
王越 , 张霞 , 许济祥 , 等 . 基于血水相关理论三期论治儿童肾病综合征并发颅内静脉窦血栓 [J]. 中国中医急症 , 2025 , 34 ( 7 ): 1188 - 1192 .
张亚达 , 陈怡人 , 唐斌擎 , 等 . 基于络病理论探讨哮喘气道重塑的病机与治疗 [J]. 上海中医药杂志 , 2025 , 59 ( 5 ): 52 - 55 .
饶毅 , 曹昺焱 , 庄威 , 等 . 《黄帝内经》分肉之间的层次探讨及该理论对针灸临床的借鉴意义 [J]. 针灸临床杂志 , 2021 , 37 ( 3 ): 1 - 5 .
张丽媛 , 程巧鸳 , 向子敬 , 等 . 高效液相色谱法测定化妆品中羟基癸酸和4种羟基酸衍生物的含量 [J]. 理化检验-化学分册 , 2026 , 62 ( 2 ): 214 - 220 .
Resch M D , Marsovszky L , Németh J , et al . Dry eye and corneal langerhans cells in systemic lupus erythematosus [J]. J Ophthalmol , 2015 , 2015 : 543835
张谦 , 万学峰 . 表皮生长因子受体抑制剂所致皮肤丘脓疱疹不良反应临床分析 [J]. 中国皮肤性病学杂志 , 2021 , 35 ( 4 ): 413 - 417, 423 .
杨培慧 , 邓丹琪 . 细胞自噬与系统性红斑狼疮发病机制研究进展 [J]. 皮肤病与性病 , 2025 , 47 ( 4 ): 223 - 228 .
王中江 , 张理涛 , 聂振华 . 系统性红斑狼疮合并泛发性扁平疣1例 [J]. 中国中西医结合皮肤性病学杂志 , 2024 , 23 ( 5 ): 451 - 452 .
朱刘畅 , 赵书山 . 固有免疫和适应性免疫在系统性红斑狼疮发病中的作用 [J]. 浙江医学 , 2025 , 47 ( 23 ): 2573 - 2576 .
程丽丽 , 黄传兵 , 汤忠富 , 等 . 芪黄健脾滋肾颗粒对系统性红斑狼疮的临床疗效及B细胞功能的影响 [J/OL]. 中国实验方剂学杂志 , 2026-02-08 . https://doi.org/10.13422/j.cnki.syfjx.20260698 https://doi.org/10.13422/j.cnki.syfjx.20260698 .
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