Exploration of Zhu Danxi's qi‑blood theory in treating "yin deficiency with dampness accumulation" in diabetes mellitus complicated by hypertension from perspective of comorbidity
LIU Yuhan,YANG Kongming,WANG Qin,et al.Exploration of Zhu Danxi's qi‑blood theory in treating "yin deficiency with dampness accumulation" in diabetes mellitus complicated by hypertension from perspective of comorbidity[J].Shanghai Journal of Traditional Chinese Medicine,2026,60(6):47-51.
LIU Yuhan,YANG Kongming,WANG Qin,et al.Exploration of Zhu Danxi's qi‑blood theory in treating "yin deficiency with dampness accumulation" in diabetes mellitus complicated by hypertension from perspective of comorbidity[J].Shanghai Journal of Traditional Chinese Medicine,2026,60(6):47-51.DOI: 10.16305/j.1007-1334.2026.z20250320003.
Based on Zhu Danxi's qi-blood theory, and focusing on the pathogenesis of "yin deficiency with dampness accumulation" in diabetes mellitus complicated by hypertension, this paper analyzes its dynamic progression. The academic viewpoint is proposed that "yin is generated in the spleen, stored in the kidneys, and used by the liver; dampness originates in the spleen, transforms in the kidneys, and is dispersed by the liver." Emphasizing the simultaneous treatment of the liver, spleen, and kidneys, a self-formulated Xiaoke basic prescription for diabetes is used to regulate the liver and benefit the kidneys, harmonize the middle to regulate qi, nourish yin and expel dampness. Satisfactory clinical efficacy has been achieved, providing a new perspective for syndrome differentiation and treatment of metabolic comorbidities in traditional Chinese medicine. A clinical case is presented for reference.
LANGENBERG C , HINGORANI A D , WHITTY C . Biological and functional multimorbidity-from mechanisms to management [J]. Nat Med , 2023 , 29 ( 7 ): 1649 - 1657 .