Based on the “Chapter 6： Blood Impediment and Deficiency Exhaustion—Pulses， Patterns and Treatment” in the traditional Chinese medicine （TCM） classic ,Synopsis of Golden Chamber,， the TCM pathogenesis and development， as well as treatment scheme of “strengthening vital qi and resolving blood stasis” of liver cirrhosis was discussed on the basis of “long-term blood impediment and accumulation of deficiency exhaustion”. At present， TCM diagnosis and treatment for liver cirrhosis is based on the pathogenesis of “amassment and accumulation” and “tympanites” and the treatment method of activating blood and resolving stasis， but the theoretical summary of clinical diagnosis and treatment is still lacking. We elaborate the TCM theory of “blood impediment leads to exhaustion， and liver exhaustion generates accumulation”， proposing that “long-term blood impediment and accumulation of deficiency exhaustion” is the basic TCM pathogenesis of liver cirrhosis， and “long-term blood impediment and intermingled stasis and heat” is the TCM pathogenesis of jaundice in liver cirrhosis. The “Blood Impediment and Deficiency Exhaustion Chapter” in ,Synopsis of Golden Chamber, has enlightened the TCM phased treatment of liver cirrhosis in the clinic.